Salubrinal Suppresses IL-17-Induced Upregulation of MMP-13 and Extracellular Matrix Degradation Thro...
Salubrinal Suppresses IL-17-Induced Upregulation of MMP-13 and Extracellular Matrix Degradation Through the NF-kB Pathway in Human Nucleus Pulposus Cells
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Author / Creator
Yao, Zhixiao , Nie, Lin , Zhao, Yunpeng , Zhang, Yuanqiang , Liu, Yi , Li, Jingkun and Cheng, Lei
Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
Matrix metalloproteinase 13 (MMP-13) plays an important role in the process of pro-inflammatory cytokine-induced intervertebral disc degeneration (IDD). This study examined the effect of IL-17 on the regulation of MMP-13 and the extracellular matrix (ECM) in the intervertebral disc (IVD). We then examined whether salubrinal, a known inhibitor of eI...
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Full title
Salubrinal Suppresses IL-17-Induced Upregulation of MMP-13 and Extracellular Matrix Degradation Through the NF-kB Pathway in Human Nucleus Pulposus Cells
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Record Identifier
TN_cdi_proquest_miscellaneous_1846421977
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846421977
Other Identifiers
ISSN
0360-3997
E-ISSN
1573-2576
DOI
10.1007/s10753-016-0435-y
