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Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1852672073

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

About this item

Full title

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2016-12, Vol.375 (22), p.2144-2153

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

Statins are known to lower levels of LDL cholesterol, protect against cardiovascular disease, and slightly increase the risk of type 2 diabetes. This analysis of genetic variants in 112,772 participants from 14 studies suggests that PCSK9 inhibitors may do the same.
Monoclonal antibodies and other therapies that inhibit proprotein convertase sub...

Alternative Titles

Full title

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1852672073

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1852672073

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1604304

How to access this item