Next-generation sequencing is highly sensitive for the detection of beta-catenin mutations in desmoi...
Next-generation sequencing is highly sensitive for the detection of beta-catenin mutations in desmoid-type fibromatoses
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Desmoid-type fibromatoses are locally aggressive and frequently recurrent tumours, and an accurate diagnosis is essential for patient management. The majority of sporadic lesions harbour beta-catenin (
CTNNB1
) mutations. We used next-generation sequencing to detect
CTNNB1
mutations and to compare the sensitivity and specificity of next...
Alternative Titles
Full title
Next-generation sequencing is highly sensitive for the detection of beta-catenin mutations in desmoid-type fibromatoses
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_1855075263
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1855075263
Other Identifiers
ISSN
0945-6317
E-ISSN
1432-2307
DOI
10.1007/s00428-015-1765-0
