Functions of bromodomain-containing proteins and their roles in homeostasis and cancer
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Key Points
Bromodomains (BRDs) are evolutionarily conserved protein–protein interaction modules. Structure-based alignments have clustered human BRDs into eight distinct families.
BRD modules share a conserved bundle of 4 α-helices (αZ, αA, αB and αC) that are linked to each other by loop segments of variable length (ZA and BC loops).
BRDs...
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Full title
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer
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TN_cdi_proquest_miscellaneous_1855789812
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1855789812
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ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm.2016.143
