An infrared spectroscopy approach to follow β-sheet formation in peptide amyloid assemblies
An infrared spectroscopy approach to follow β-sheet formation in peptide amyloid assemblies
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Amyloidogenic peptides and proteins play a crucial role in a variety of neurodegenerative disorders such as Alzheimer's and Parkinson's disease. These proteins undergo a spontaneous transition from a soluble, often partially folded form, into insoluble amyloid fibrils that are rich in β-sheets. Increasing evidence suggests that highly dynamic, poly...
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An infrared spectroscopy approach to follow β-sheet formation in peptide amyloid assemblies
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TN_cdi_proquest_miscellaneous_1859483191
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859483191
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.2615