Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
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Author / Creator
Kagan, Valerian E , Mao, Gaowei , Qu, Feng , Angeli, Jose Pedro Friedmann , Doll, Sebastian , Croix, Claudette St , Dar, Haider Hussain , Liu, Bing , Tyurin, Vladimir A , Ritov, Vladimir B , Kapralov, Alexandr A , Amoscato, Andrew A , Jiang, Jianfei , Anthonymuthu, Tamil , Mohammadyani, Dariush , Yang, Qin , Proneth, Bettina , Klein-Seetharaman, Judith , Watkins, Simon , Bahar, Ivet , Greenberger, Joel , Mallampalli, Rama K , Stockwell, Brent R , Tyurina, Yulia Y , Conrad, Marcus and Bayır, Hülya
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Arachidonyl and adrenoyl PE phospholipids generated by ACSL4, an acyl-CoA synthase, are doubly or triply oxidized by lipoxygenases and other iron-containing sources of oxidation to promote ferroptotic cell death.
Enigmatic lipid peroxidation products have been claimed as the proximate executioners of ferroptosis—a specialized death program trigg...
Alternative Titles
Full title
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
Authors, Artists and Contributors
Author / Creator
Mao, Gaowei
Qu, Feng
Angeli, Jose Pedro Friedmann
Doll, Sebastian
Croix, Claudette St
Dar, Haider Hussain
Liu, Bing
Tyurin, Vladimir A
Ritov, Vladimir B
Kapralov, Alexandr A
Amoscato, Andrew A
Jiang, Jianfei
Anthonymuthu, Tamil
Mohammadyani, Dariush
Yang, Qin
Proneth, Bettina
Klein-Seetharaman, Judith
Watkins, Simon
Bahar, Ivet
Greenberger, Joel
Mallampalli, Rama K
Stockwell, Brent R
Tyurina, Yulia Y
Conrad, Marcus
Bayır, Hülya
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1859484507
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859484507
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2238