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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859484507

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Arachidonyl and adrenoyl PE phospholipids generated by ACSL4, an acyl-CoA synthase, are doubly or triply oxidized by lipoxygenases and other iron-containing sources of oxidation to promote ferroptotic cell death.
Enigmatic lipid peroxidation products have been claimed as the proximate executioners of ferroptosis—a specialized death program trigg...

Alternative Titles

Full title

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1859484507

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859484507

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.2238

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