A novel synthetic derivative of squamosamide FLZ inhibits the high mobility group box 1 protein-medi...
A novel synthetic derivative of squamosamide FLZ inhibits the high mobility group box 1 protein-mediated neuroinflammatory responses in murine BV2 microglial cells
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Berlin/Heidelberg: Springer Berlin Heidelberg
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English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
High mobility group box 1 (HMGB1) is a critical pro-inflammatory cytokine that contributes to the pathogenesis of various human diseases. FLZ, a squamosamide derivative, has been demonstrated to have neuroprotective effects in Parkinson’s disease models and shows strong anti-inflammatory activity, while the precise mechanism remains unclear. Here,...
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A novel synthetic derivative of squamosamide FLZ inhibits the high mobility group box 1 protein-mediated neuroinflammatory responses in murine BV2 microglial cells
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TN_cdi_proquest_miscellaneous_1876497836
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1876497836
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ISSN
0028-1298
E-ISSN
1432-1912
DOI
10.1007/s00210-017-1363-6
