Analysis of the Structural Stability Among Cyclotide Members Through Cystine Knot Fold that Underpin...
Analysis of the Structural Stability Among Cyclotide Members Through Cystine Knot Fold that Underpins Its Potential Use as a Drug Scaffold
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Dordrecht: Springer Netherlands
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English
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Dordrecht: Springer Netherlands
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Recent emergence of plant derived peptide cyclotides, characterized with a cyclized head-to-tail backbone and three disulfide bonds forming cyclic cystine knot, has advanced the field of biopharmaceutics to next level. This conserved structural feature of cyclotides holds responsible for its outstanding resistance towards thermal, chemical and enzy...
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Analysis of the Structural Stability Among Cyclotide Members Through Cystine Knot Fold that Underpins Its Potential Use as a Drug Scaffold
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TN_cdi_proquest_miscellaneous_1877850108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1877850108
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ISSN
1573-3149
E-ISSN
1573-3904
DOI
10.1007/s10989-016-9537-5