Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK p...
Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways
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Publisher
Milan: Springer Milan
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Language
English
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Publisher
Milan: Springer Milan
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Aims
Calcific aortic valve disease (CAVD) affects 2–6% of the population over 65 years, and age, gender, smoking, overweight, dyslipidemia, diabetes contribute to the development of this disease. CAVD results, in part, from the osteoblast differentiation of human valvular interstitial cells (VICs). This study aims to elucidate the effects of lep...
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Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways
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TN_cdi_proquest_miscellaneous_1878821144
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1878821144
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ISSN
0940-5429
E-ISSN
1432-5233
DOI
10.1007/s00592-017-0980-3