Targeting glutamate signalling in depression: progress and prospects
Targeting glutamate signalling in depression: progress and prospects
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Author / Creator
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Depression is one of the leading causes of disability worldwide; however, no truly mechanistically novel compounds have come to the market in decades.
Ignited by the observation of a rapid antidepressant effect of the glutamate
N
-methyl-
D
-aspartate (NMDA) receptor antagonist ketamine, the glutamate system has emerged...
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Full title
Targeting glutamate signalling in depression: progress and prospects
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TN_cdi_proquest_miscellaneous_1878822195
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1878822195
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd.2017.16