Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow
Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Longden
et al
. demonstrate that brain capillaries function as a vast sensory web, monitoring neuronal activity by sensing K
+
and translating this into a K
IR
-channel-mediated regenerative retrograde hyperpolarizing signal that propagates to upstream arterioles to drive vasodilation and an increase in blood flow into the capilla...
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Full title
Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow
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TN_cdi_proquest_miscellaneous_1879661355
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1879661355
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.4533
