Visualization and targeting of LGR5+ human colon cancer stem cells
Visualization and targeting of LGR5+ human colon cancer stem cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The cancer stem cell (CSC) theory highlights a self-renewing subpopulation of cancer cells that fuels tumour growth. The existence of human CSCs is mainly supported by xenotransplantation of prospectively isolated cells, but their clonal dynamics and plasticity remain unclear. Here, we show that human LGR5
+
colorectal cancer cells serve as C...
Alternative Titles
Full title
Visualization and targeting of LGR5+ human colon cancer stem cells
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TN_cdi_proquest_miscellaneous_1882500035
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1882500035
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature22081
