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Prevention of Axonal Degeneration by Perineurium Injection of Mitochondria in a Sciatic Nerve Crush...

Prevention of Axonal Degeneration by Perineurium Injection of Mitochondria in a Sciatic Nerve Crush...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1883179974

Prevention of Axonal Degeneration by Perineurium Injection of Mitochondria in a Sciatic Nerve Crush Injury Model

About this item

Full title

Prevention of Axonal Degeneration by Perineurium Injection of Mitochondria in a Sciatic Nerve Crush Injury Model

Publisher

United States: Oxford University Press

Journal title

Neurosurgery, 2017-03, Vol.80 (3), p.475-488

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Abstract
BACKGROUND: Axon degeneration leads to cytoskeletal disassembly, metabolism imbalance, and mitochondrial dysfunction during neurodegeneration or nerve injury.
OBJECTIVE: In this study, we assess the possibility of mitigating axon degeneration by local injection of mitochondria in a crushed sciatic nerve.
METHODS: Sciatic nerve exp...

Alternative Titles

Full title

Prevention of Axonal Degeneration by Perineurium Injection of Mitochondria in a Sciatic Nerve Crush Injury Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1883179974

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1883179974

Other Identifiers

ISSN

0148-396X

E-ISSN

1524-4040

DOI

10.1093/neuros/nyw090

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