Membrane Association of Myotubularin-Related Protein 2 Is Mediated by a Pleckstrin Homology-GRAM Dom...
Membrane Association of Myotubularin-Related Protein 2 Is Mediated by a Pleckstrin Homology-GRAM Domain and a Coiled-Coil Dimerization Module
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Mutations in the myotubularin (MTM)-related protein 2 (MTMR2) gene are responsible for the severe autosomal recessive neuropathy Charcot-Marie-Tooth disease type 4B1. MTMR2 belongs to the MTM family of dual-specific phosphatases that use phosphatidylinositol (PI) 3,5-bisphosphate [PI(3,5)P2] and PI 3-phosphate [PI(3)P] as their substrate. Because t...
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Full title
Membrane Association of Myotubularin-Related Protein 2 Is Mediated by a Pleckstrin Homology-GRAM Domain and a Coiled-Coil Dimerization Module
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TN_cdi_proquest_miscellaneous_18881577
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18881577
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2132732100
