Biological and clinical consequences of NPM1 mutations in AML
Biological and clinical consequences of NPM1 mutations in AML
About this item
Full title
Author / Creator
Heath, E M , Chan, S M , Minden, M D , Murphy, T , Shlush, L I and Schimmer, A D
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Acute myeloid leukemia (AML) is characterized by accumulation of myeloid cells in the bone marrow because of impaired differentiation and proliferation, resulting in hematopoietic insufficiency.
NPM1
is one of the most commonly mutated genes in AML, present in 20–30% of cases. Mutations in
NPM1
represent a distinct entity in the World H...
Alternative Titles
Full title
Biological and clinical consequences of NPM1 mutations in AML
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1891855142
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1891855142
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2017.30
