Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through up...
Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle
About this item
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Author / Creator
Misu, Hirofumi , Takayama, Hiroaki , Saito, Yoshiro , Mita, Yuichiro , Kikuchi, Akihiro , Ishii, Kiyo-aki , Chikamoto, Keita , Kanamori, Takehiro , Tajima, Natsumi , Lan, Fei , Takeshita, Yumie , Honda, Masao , Tanaka, Mutsumi , Kato, Seiji , Matsuyama, Naoto , Yoshioka, Yuya , Iwayama, Kaito , Tokuyama, Kumpei , Akazawa, Nobuhiko , Maeda, Seiji , Takekoshi, Kazuhiro , Matsugo, Seiichi , Noguchi, Noriko , Kaneko, Shuichi and Takamura, Toshinari
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Selenoprotein P is released from the liver and acts through LRP1 in the muscle to contribute to exercise resistance in mouse and man by inhibiting ROS levels via inhibition of AMPK and PGC-1α.
Exercise has numerous health-promoting effects in humans
1
; however, individual responsiveness to exercise with regard to endurance or metabolic he...
Alternative Titles
Full title
Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle
Authors, Artists and Contributors
Author / Creator
Takayama, Hiroaki
Saito, Yoshiro
Mita, Yuichiro
Kikuchi, Akihiro
Ishii, Kiyo-aki
Chikamoto, Keita
Kanamori, Takehiro
Tajima, Natsumi
Lan, Fei
Takeshita, Yumie
Honda, Masao
Tanaka, Mutsumi
Kato, Seiji
Matsuyama, Naoto
Yoshioka, Yuya
Iwayama, Kaito
Tokuyama, Kumpei
Akazawa, Nobuhiko
Maeda, Seiji
Takekoshi, Kazuhiro
Matsugo, Seiichi
Noguchi, Noriko
Kaneko, Shuichi
Takamura, Toshinari
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1891873429
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1891873429
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4295
