Pre-metastatic niches: organ-specific homes for metastases
Pre-metastatic niches: organ-specific homes for metastases
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Author / Creator
Peinado, Héctor , Zhang, Haiying , Matei, Irina R. , Costa-Silva, Bruno , Hoshino, Ayuko , Rodrigues, Goncalo , Psaila, Bethan , Kaplan, Rosandra N. , Bromberg, Jacqueline F. , Kang, Yibin , Bissell, Mina J. , Cox, Thomas R. , Giaccia, Amato J. , Erler, Janine T. , Hiratsuka, Sachie , Ghajar, Cyrus M. and Lyden, David
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
Organs of future metastasis are selectively and actively modified by the primary tumour before metastatic spread has occurred.
Tumours induce the formation of microenvironments in distant organs that are conducive to the survival and outgrowth of tumour cells before their arrival at these sites. These microenvironments are termed p...
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Full title
Pre-metastatic niches: organ-specific homes for metastases
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TN_cdi_proquest_miscellaneous_1897373665
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1897373665
Other Identifiers
ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc.2017.6
