The microbiota regulates type 2 immunity through RORγt+T cells
The microbiota regulates type 2 immunity through RORγt+T cells
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Author / Creator
Ohnmacht, Caspar , Park, Joo-Hong , Cording, Sascha , Wing, James B. , Atarashi, Koji , Obata, Yuuki , Gaboriau-Routhiau, Valérie , Marques, Rute , Dulauroy, Sophie , Fedoseeva, Maria , Busslinger, Meinrad , Cerf-Bensussan, Nadine , Boneca, Ivo G. , Voehringer, David , Hase, Koji , Honda, Kenya , Sakaguchi, Shimon and Eberl, Gérard
Publisher
American Association for the Advancement of Science
Journal title
Language
English
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Publisher
American Association for the Advancement of Science
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Scope and Contents
Contents
Changes to the symbiotic microbiota early in life, or the absence of it, can lead to exacerbated type 2 immunity and allergic inflammations. Although it is unclear how the microbiota regulates type 2 immunity, it is a strong inducer of proinflammatory T helper 17 (TH17) cells and regulatory T cells (Tregs) in the intestine. Here, we report that mic...
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Full title
The microbiota regulates type 2 immunity through RORγt+T cells
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Record Identifier
TN_cdi_proquest_miscellaneous_1904214188
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904214188
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aac4263
