Uncovering disease-disease relationships through the incomplete interactome
Uncovering disease-disease relationships through the incomplete interactome
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Publisher
Washington: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington: American Association for the Advancement of Science
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Scope and Contents
Contents
Shared genes represent a powerful but limited representation of the mechanistic relationship between two diseases. However, the analysis of protein-protein interactions has been hampered by the incompleteness of interactome maps. Menche
et al.
formulated the mathematical conditions needed to allow a disease module (a localized region of conne...
Alternative Titles
Full title
Uncovering disease-disease relationships through the incomplete interactome
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TN_cdi_proquest_miscellaneous_1904238517
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904238517
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1257601