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Uncovering disease-disease relationships through the incomplete interactome

Uncovering disease-disease relationships through the incomplete interactome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904238517

Uncovering disease-disease relationships through the incomplete interactome

About this item

Full title

Uncovering disease-disease relationships through the incomplete interactome

Publisher

Washington: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2015-02, Vol.347 (6224), p.841-841

Language

English

Formats

Publication information

Publisher

Washington: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Shared genes represent a powerful but limited representation of the mechanistic relationship between two diseases. However, the analysis of protein-protein interactions has been hampered by the incompleteness of interactome maps. Menche
et al.
formulated the mathematical conditions needed to allow a disease module (a localized region of conne...

Alternative Titles

Full title

Uncovering disease-disease relationships through the incomplete interactome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1904238517

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904238517

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1257601

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