Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The structure of Cpf1, a CRISPR–Cas/RNA-guided nuclease, is presented with a three-stranded RNA–DNA loop after cleavage, providing insight into its working mechanism.
Structure of a post-cleavage Cpf1 complex
The CRISPR–Cas9 system for genome editing has evolved to utilize variants of Cas9-type enzymes that possess different properties. One o...
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Full title
Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
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TN_cdi_proquest_miscellaneous_1904908761
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904908761
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature22398
