Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer a...
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
A protocol based on chemical modulation of WNT activity is used to efficiently generate colonic organoids that recapitulate the molecular features of human colon tissue. Colonic organoids generated from induced pluripotent stem cells from patients with familial adenomatous polyposis provide an
in vitro
platform for disease modeling and precli...
Alternative Titles
Full title
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_1911202991
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1911202991
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4355
