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MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals...

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1911618740

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

About this item

Full title

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2017-06, Vol.23 (6), p.723-732

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The scavenger receptor MSR1 contributes to the clearance of damage-associated molecular patterns (DAMPs) by infiltrating myeloid cells in the post-stroke rodent brain. Myeloid cell MSR1 deficiency impairs clearance and exacerbates stroke-induced impairments, whereas a pharmacological intervention to boost MSR1 expression improves pathological and f...

Alternative Titles

Full title

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1911618740

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1911618740

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.4312

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