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Myelin regulatory factor drives remyelination in multiple sclerosis

Myelin regulatory factor drives remyelination in multiple sclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1911708217

Myelin regulatory factor drives remyelination in multiple sclerosis

About this item

Full title

Myelin regulatory factor drives remyelination in multiple sclerosis

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2017-09, Vol.134 (3), p.403-422

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Remyelination is limited in the majority of multiple sclerosis (MS) lesions despite the presence of oligodendrocyte precursor cells (OPCs) in most lesions. This observation has led to the view that a failure of OPCs to fully differentiate underlies remyelination failure. OPC differentiation requires intricate transcriptional regulation, which may b...

Alternative Titles

Full title

Myelin regulatory factor drives remyelination in multiple sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1911708217

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1911708217

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-017-1741-7

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