DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acu...
DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia
About this item
Full title
Author / Creator
Gaidzik, V I , Weber, D , Paschka, P , Kaumanns, A , Krieger, S , Corbacioglu, A , Krönke, J , Kapp-Schwoerer, S , Krämer, D , Horst, H-A , Schmidt-Wolf, I , Held, G , Kündgen, A , Ringhoffer, M , Götze, K , Kindler, T , Fiedler, W , Wattad, M , Schlenk, R F , Bullinger, L , Teleanu, V , Schlegelberger, B , Thol, F , Heuser, M , Ganser, A , Döhner, H , Döhner, K , German-Austrian Acute Myeloid Leukemia Study Group (AMLSG) and for the German-Austrian Acute Myeloid Leukemia Study Group (AMLSG)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
We investigated the prognostic impact of minimal residual disease (MRD) monitoring in acute myeloid leukemia patients harboring
DNA methyltransferase 3A-
R882H/-R882C mutations (
DNMT3A
mut
). MRD was determined by real-time quantitative PCR (RQ-PCR) in 1494 samples of 181
DNMT3A
mut
patients. At the time of diagnosis,
DN...
Alternative Titles
Full title
DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia
Authors, Artists and Contributors
Author / Creator
Weber, D
Paschka, P
Kaumanns, A
Krieger, S
Corbacioglu, A
Krönke, J
Kapp-Schwoerer, S
Krämer, D
Horst, H-A
Schmidt-Wolf, I
Held, G
Kündgen, A
Ringhoffer, M
Götze, K
Kindler, T
Fiedler, W
Wattad, M
Schlenk, R F
Bullinger, L
Teleanu, V
Schlegelberger, B
Thol, F
Heuser, M
Ganser, A
Döhner, H
Döhner, K
German-Austrian Acute Myeloid Leukemia Study Group (AMLSG)
for the German-Austrian Acute Myeloid Leukemia Study Group (AMLSG)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1913399189
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1913399189
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2017.200