Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibi...
Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibility to malaria
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Publisher
National Academy of Sciences
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Language
English
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Publisher
National Academy of Sciences
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Contents
Polygenic autoimmune diseases, such as systemic lupus erythematosus (SLE), are a significant cause of morbidity and mortality worldwide. In recent years, functionally important genetic polymorphisms conferring susceptibility to SLE have been identified, but the evolutionary pressures driving their retention in the gene pool remain elusive. A defunc...
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Full title
Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibility to malaria
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TN_cdi_proquest_miscellaneous_19295668
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19295668
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0608889104