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Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibi...

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19295668

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibility to malaria

About this item

Full title

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibility to malaria

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (17), p.7169-7174

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

Polygenic autoimmune diseases, such as systemic lupus erythematosus (SLE), are a significant cause of morbidity and mortality worldwide. In recent years, functionally important genetic polymorphisms conferring susceptibility to SLE have been identified, but the evolutionary pressures driving their retention in the gene pool remain elusive. A defunc...

Alternative Titles

Full title

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibility to malaria

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19295668

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19295668

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0608889104

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