Role and Timing of GTP Binding and Hydrolysis during EF-G-Dependent tRNA Translocation on the Riboso...
Role and Timing of GTP Binding and Hydrolysis during EF-G-Dependent tRNA Translocation on the Ribosome
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The translocation of tRNA and mRNA through the ribosome is promoted by elongation factor G (EF-G), a GTPase that hydrolyzes GTP during the reaction. Recently, it was reported that, in contrast to previous observations, the affinity of EF-G was much weaker for GTP than for GDP and that ribosome-catalyzed GDP-GTP exchange would be required for transl...
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Full title
Role and Timing of GTP Binding and Hydrolysis during EF-G-Dependent tRNA Translocation on the Ribosome
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TN_cdi_proquest_miscellaneous_19325655
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19325655
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0606099103
