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CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation

CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1937761777

CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation

About this item

Full title

CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Nature methods, 2017-10, Vol.14 (10), p.963-966

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Blue-light-inducible CRISPR-based transcriptional activation systems achieve high enough endogenous gene expression to trigger the differentiation of iPSCs.
Our improved CRISPR–Cas9-based photoactivatable transcription systems, CPTS2.0 and Split-CPTS2.0, enable high blue-light-inducible activation of endogenous target genes in various human cell...

Alternative Titles

Full title

CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1937761777

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1937761777

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/nmeth.4430

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