CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation
CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Blue-light-inducible CRISPR-based transcriptional activation systems achieve high enough endogenous gene expression to trigger the differentiation of iPSCs.
Our improved CRISPR–Cas9-based photoactivatable transcription systems, CPTS2.0 and Split-CPTS2.0, enable high blue-light-inducible activation of endogenous target genes in various human cell...
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CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation
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TN_cdi_proquest_miscellaneous_1937761777
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1937761777
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.4430