Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
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Author / Creator
Ljubetič, Ajasja , Lapenta, Fabio , Gradišar, Helena , Drobnak, Igor , Aupič, Jana , Strmšek, Žiga , Lainšček, Duško , Hafner-Bratkovič, Iva , Majerle, Andreja , Krivec, Nuša , Benčina, Mojca , Pisanski, Tomaž , Veličković, Tanja Ćirković , Round, Adam , Carazo, José María , Melero, Roberto and Jerala, Roman
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Protein origami using coiled-coil building blocks produces self-assembling polyhedral cages for diverse applications.
Polypeptides and polynucleotides are natural programmable biopolymers that can self-assemble into complex tertiary structures. We describe a system analogous to designed DNA nanostructures in which protein coiled-coil (CC) dimers...
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Full title
Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
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Record Identifier
TN_cdi_proquest_miscellaneous_1951562391
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1951562391
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.3994
