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Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in...

Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19532316

Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Transgenic Mice Expressing Mutant A53T [alpha]-Synuclein

About this item

Full title

Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Transgenic Mice Expressing Mutant A53T [alpha]-Synuclein

Publisher

New York: Springer Nature B.V

Journal title

Neurochemical research, 2008-05, Vol.33 (5), p.902-911

Language

English

Formats

Publication information

Publisher

New York: Springer Nature B.V

More information

Scope and Contents

Contents

Familial Parkinson's disease (PD) has been linked to point mutations and duplication of the α-synuclein gene and mutant α-synuclein expression increases the vulnerability of neurons to exogenous insults. In this study, we analyzed the levels of dopamine and its metabolites in the olfactory bulb (OB), and nigrostriatal regions of transgenic mice exp...

Alternative Titles

Full title

Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Transgenic Mice Expressing Mutant A53T [alpha]-Synuclein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19532316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19532316

Other Identifiers

ISSN

0364-3190

E-ISSN

1573-6903

DOI

10.1007/s11064-007-9533-4

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