Trafficking in Alzheimer’s Disease: Modulation of APP Transport and Processing by the Transmembrane...
Trafficking in Alzheimer’s Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin
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New York: Springer US
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English
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New York: Springer US
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Contents
The amyloid precursor protein (APP), one key player in Alzheimer’s disease (AD), is extensively processed by different proteases. This leads to the generation of diverging fragments including the amyloid β (Aβ) peptide, which accumulates in brains of AD patients. Subcellular trafficking of APP is an important aspect for its proteolytic conversion,...
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Full title
Trafficking in Alzheimer’s Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin
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TN_cdi_proquest_miscellaneous_1957485714
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1957485714
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-017-0806-x
