Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate proces...
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Contents
We present an atomic model of a substrate-bound inner mitochondrial membrane AAA+ quality control protease in yeast, YME1. Our ~3.4-angstrom cryo-electron microscopy structure reveals how the adenosine triphosphatases (ATPases) form a closed spiral staircase encircling an unfolded substrate, directing it toward the flat, symmetric protease ring. Th...
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Full title
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing
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TN_cdi_proquest_miscellaneous_1961033127
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1961033127
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aao0464
