Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane i...
Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Ca²⁺-ATPase of skeletal muscle sarcoplasmic reticulum is an ATP-driven Ca²⁺ pump consisting of three cytoplasmic domains and 10 transmembrane helices. In the absence of Ca²⁺, the three cytoplasmic domains gather to form a compact headpiece, but the ATPase is unstable without an inhibitor. Here we describe the crystal structures of Ca²⁺-ATPase in th...
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Full title
Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors
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TN_cdi_proquest_miscellaneous_19659586
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19659586
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0700979104
