Host DNases prevent vascular occlusion by neutrophil extracellular traps
Host DNases prevent vascular occlusion by neutrophil extracellular traps
About this item
Full title
Author / Creator
Jiménez-Alcázar, Miguel , Rangaswamy, Chandini , Panda, Rachita , Bitterling, Josephine , Simsek, Yashin J. , Long, Andy T. , Bilyy, Rostyslav , Krenn, Veit , Renné, Christoph , Renné, Thomas , Kluge, Stefan , Panzer, Ulf , Mizuta, Ryushin , Mannherz, Hans Georg , Kitamura, Daisuke , Herrmann, Martin , Napirei, Markus and Fuchs, Tobias A.
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Platelet and fibrin clots occlude blood vessels in hemostasis and thrombosis. Here we report a noncanonical mechanism for vascular occlusion based on neutrophil extracellular traps (NETs), DNA fibers released by neutrophils during inflammation. We investigated which host factors control NETs in vivo and found that two deoxyribonucleases (DNases), D...
Alternative Titles
Full title
Host DNases prevent vascular occlusion by neutrophil extracellular traps
Authors, Artists and Contributors
Author / Creator
Rangaswamy, Chandini
Panda, Rachita
Bitterling, Josephine
Simsek, Yashin J.
Long, Andy T.
Bilyy, Rostyslav
Krenn, Veit
Renné, Christoph
Renné, Thomas
Kluge, Stefan
Panzer, Ulf
Mizuta, Ryushin
Mannherz, Hans Georg
Kitamura, Daisuke
Herrmann, Martin
Napirei, Markus
Fuchs, Tobias A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1971655362
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1971655362
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aam8897
