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Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-β 1-42 Analysis Results

Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-β 1-42 Analysis Results

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1973455407

Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-β 1-42 Analysis Results

About this item

Full title

Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-β 1-42 Analysis Results

Publisher

England: Oxford University Press

Journal title

Clinical chemistry (Baltimore, Md.), 2018-03, Vol.64 (3), p.576-585

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Low cerebrospinal fluid (CSF) amyloid-β 1-42 (Aβ 1-42) concentrations indicate amyloid plaque accumulation in the brain, a pathological hallmark of Alzheimer disease (AD). Innotest assay values of Aβ 1-42 have gradually increased over the past 2 decades, which might lead to misclassification of AD when a single cutpoint for abnormality is used. We...

Alternative Titles

Full title

Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-β 1-42 Analysis Results

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1973455407

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1973455407

Other Identifiers

ISSN

0009-9147

E-ISSN

1530-8561

DOI

10.1373/clinchem.2017.281055

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