Metabolic Engineering of a Genetic Selection System with Tunable Stringency
Metabolic Engineering of a Genetic Selection System with Tunable Stringency
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The biosynthesis of small molecules can be fine-tuned by (re)engineering metabolic flux within cells. We have adapted this approach to optimize an in vivo selection system for the conversion of prephenate to phenylpyruvate, a key step in the production of the essential aromatic amino acid phenylalanine. Careful control of prephenate concentration i...
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Full title
Metabolic Engineering of a Genetic Selection System with Tunable Stringency
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TN_cdi_proquest_miscellaneous_19745137
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19745137
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0705379104
