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Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Be...

Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Be...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19808324

Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis

About this item

Full title

Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2005-07, Vol.353 (4), p.369-374

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

A 46-year-old woman with multiple sclerosis died from progressive multifocal leukoencephalopathy after receiving 37 doses of natalizumab plus interferon beta-1a as part of a clinical trial. At autopsy, there were diffuse macroscopic and microscopic PML lesions. JC virus was identified in cerebrospinal fluid before death and in brain tissue at autop...

Alternative Titles

Full title

Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19808324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19808324

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa051782

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