Structure of a human catalytic step I spliceosome
Structure of a human catalytic step I spliceosome
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Publisher
United States: The American Association for the Advancement of Science
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Language
English
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United States: The American Association for the Advancement of Science
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Scope and Contents
Contents
Splicing by the spliceosome involves branching and exon ligation. The branching reaction leads to the formation of the catalytic step I spliceosome (C complex). Here we report the cryo-electron microscopy structure of the human C complex at an average resolution of 4.1 angstroms. Compared with the
C complex, the human complex contains 11 additio...
Alternative Titles
Full title
Structure of a human catalytic step I spliceosome
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Record Identifier
TN_cdi_proquest_miscellaneous_1989537506
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1989537506
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aar6401