Phase separation of a yeast prion protein promotes cellular fitness
Phase separation of a yeast prion protein promotes cellular fitness
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Publisher
United States: The American Association for the Advancement of Science
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Language
English
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Publisher
United States: The American Association for the Advancement of Science
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Contents
Despite the important role of prion domains in neurodegenerative disease, their physiological function has remained enigmatic. Previous work with yeast prions has defined prion domains as sequences that form self-propagating aggregates. Here, we uncovered an unexpected function of the canonical yeast prion protein Sup35. In stressed conditions, Sup...
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Full title
Phase separation of a yeast prion protein promotes cellular fitness
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Record Identifier
TN_cdi_proquest_miscellaneous_1989538005
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1989538005
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aao5654
