Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics...
Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The master transactivator CIITA is essential to the regulation of Major Histocompatibility Complex (MHC)class II genes and an effective immune response. CIITA is known to modulate a small number of non-MHC genes involved in antigen presentation such as CD74 and B2M but its broader genome-wide function and relationship with underlying genetic divers...
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Full title
Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach
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TN_cdi_proquest_miscellaneous_2000181140
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000181140
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ISSN
1474-760X
E-ISSN
1474-760X
DOI
10.1186/s13059-014-0494-z
