Somatic structural rearrangements in genetically engineered mouse mammary tumors
Somatic structural rearrangements in genetically engineered mouse mammary tumors
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Here we present the first paired-end sequencing of tumors from genetically engineered mouse models of cancer to determine how faithfully these models recapitulate the landscape of somatic rearrangements found in human tumors. These were models of Trp53-mutated breast cancer, Brca1- and Brca2-associated hereditary breast cancer, and E-cadherin (Cdh1...
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Full title
Somatic structural rearrangements in genetically engineered mouse mammary tumors
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TN_cdi_proquest_miscellaneous_2000187418
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000187418
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ISSN
1474-760X
E-ISSN
1474-760X
DOI
10.1186/gb-2010-11-10-r100
