The importance of study design for detecting differentially abundant features in high-throughput exp...
The importance of study design for detecting differentially abundant features in high-throughput experiments
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
High-throughput assays, such as RNA-seq, to detect differential abundance are widely used. Variable performance across statistical tests, normalizations, and conditions leads to resource wastage and reduced sensitivity. EDDA represents a first, general design tool for RNA-seq, Nanostring, and metagenomic analysis, that rationally selects tests, pre...
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Full title
The importance of study design for detecting differentially abundant features in high-throughput experiments
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TN_cdi_proquest_miscellaneous_2000197508
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000197508
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ISSN
1474-760X
E-ISSN
1474-760X
DOI
10.1186/s13059-014-0527-7
