mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
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Author / Creator
Cheng, Shih-Chin , Quintin, Jessica , Cramer, Robert A. , Shepardson, Kelly M. , Saeed, Sadia , Kumar, Vinod , Giamarellos-Bourboulis, Evangelos J. , Martens, Joost H. A. , Rao, Nagesha Appukudige , Aghajanirefah, Ali , Manjeri, Ganesh R. , Li, Yang , Ifrim, Daniela C. , Arts, Rob J. W. , van der Meer, Brian M. J. W. , Deen, Peter M. T. , Logie, Colin , O’Neill, Luke A. , Willems, Peter , van de Veerdonk, Frank L. , van der Meer, Jos W. M. , Ng, Aylwin , Joosten, Leo A. B. , Wijmenga, Cisca , Stunnenberg, Hendrik G. , Xavier, Ramnik J. and Netea, Mihai G.
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Epigenetic reprogramming of myeloid cells, also known as trained immunity, confers nonspecific protection from secondary infections. Using histone modification profiles of human monocytes trained with the Candida albicans cell wall constituent β-glucan, together with a genome-wide transcriptome, we identified the induced expression of genes involve...
Alternative Titles
Full title
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
Authors, Artists and Contributors
Author / Creator
Quintin, Jessica
Cramer, Robert A.
Shepardson, Kelly M.
Saeed, Sadia
Kumar, Vinod
Giamarellos-Bourboulis, Evangelos J.
Martens, Joost H. A.
Rao, Nagesha Appukudige
Aghajanirefah, Ali
Manjeri, Ganesh R.
Li, Yang
Ifrim, Daniela C.
Arts, Rob J. W.
van der Meer, Brian M. J. W.
Deen, Peter M. T.
Logie, Colin
O’Neill, Luke A.
Willems, Peter
van de Veerdonk, Frank L.
van der Meer, Jos W. M.
Ng, Aylwin
Joosten, Leo A. B.
Wijmenga, Cisca
Stunnenberg, Hendrik G.
Xavier, Ramnik J.
Netea, Mihai G.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2000377022
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000377022
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1250684
