Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes
Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes
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Author / Creator
Zhang, Mengyun , Dong, Yong , Hu, Fangxiao , Yang, Dan , Zhao, Qianhao , Lv, Cui , Wang, Ying , Xia, Chengxiang , Weng, Qitong , Liu, Xiaofei , Li, Chen , Zhou, Peiqing , Wang, Tongjie , Guan, Yuxian , Guo, Rongqun , Liu, Lijuan , Geng, Yang , Wu, Hongling , Du, Juan , Hu, Zheng , Xu, Sheng , Chen, Jiekai , He, Aibin , Liu, Bing , Wang, Demin , Yang, Yong-Guang and Wang, Jinyong
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Deletion of master regulators of the B cell lineage reprograms B cells into T cells. Here we found that the transcription factor Hoxb5, which is expressed in uncommitted hematopoietic progenitor cells but is not present in cells committed to the B cell or T cell lineage, was able to reprogram pro-pre-B cells into functional early T cell lineage pro...
Alternative Titles
Full title
Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes
Authors, Artists and Contributors
Author / Creator
Dong, Yong
Hu, Fangxiao
Yang, Dan
Zhao, Qianhao
Lv, Cui
Wang, Ying
Xia, Chengxiang
Weng, Qitong
Liu, Xiaofei
Li, Chen
Zhou, Peiqing
Wang, Tongjie
Guan, Yuxian
Guo, Rongqun
Liu, Lijuan
Geng, Yang
Wu, Hongling
Du, Juan
Hu, Zheng
Xu, Sheng
Chen, Jiekai
He, Aibin
Liu, Bing
Wang, Demin
Yang, Yong-Guang
Wang, Jinyong
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2001914150
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2001914150
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0046-x
