Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration
Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
Rictor associates with mTOR to form the mTORC2 complex, which activity regulates neuronal function and survival. Neurodegenerative diseases are characterized by the presence of neuronal dysfunction and cell death in specific brain regions such as for example Huntington’s disease (HD), which is characterized by the loss of striatal projection neuron...
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Full title
Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration
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TN_cdi_proquest_miscellaneous_2007116790
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2007116790
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-018-0956-5
