Lactate in the brain: from metabolic end-product to signalling molecule
Lactate in the brain: from metabolic end-product to signalling molecule
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Much research has shown that lactate produced by astrocytes serves as a neuronal energy substrate. In this Review, Magistretti and Allaman describe this model as well as recent evidence that lactate also modulates neuronal properties, including excitability and plasticity, thus helping to set the 'homeostatic tone' of the nervous system.
Lactate...
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Lactate in the brain: from metabolic end-product to signalling molecule
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TN_cdi_proquest_miscellaneous_2012117470
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2012117470
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ISSN
1471-003X
E-ISSN
1471-0048,1469-3178
DOI
10.1038/nrn.2018.19