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Lactate in the brain: from metabolic end-product to signalling molecule

Lactate in the brain: from metabolic end-product to signalling molecule

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2012117470

Lactate in the brain: from metabolic end-product to signalling molecule

About this item

Full title

Lactate in the brain: from metabolic end-product to signalling molecule

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Neuroscience, 2018-04, Vol.19 (4), p.235-249

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Much research has shown that lactate produced by astrocytes serves as a neuronal energy substrate. In this Review, Magistretti and Allaman describe this model as well as recent evidence that lactate also modulates neuronal properties, including excitability and plasticity, thus helping to set the 'homeostatic tone' of the nervous system.
Lactate...

Alternative Titles

Full title

Lactate in the brain: from metabolic end-product to signalling molecule

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2012117470

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2012117470

Other Identifiers

ISSN

1471-003X

E-ISSN

1471-0048,1469-3178

DOI

10.1038/nrn.2018.19

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