Colorimetric determination of the activity of alkaline phosphatase based on the use of Cu(II)-modula...
Colorimetric determination of the activity of alkaline phosphatase based on the use of Cu(II)-modulated G-quadruplex-based DNAzymes
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Publisher
Vienna: Springer Vienna
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Language
English
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Publisher
Vienna: Springer Vienna
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Scope and Contents
Contents
A colorimetric detection scheme is introduced for the determination of alkaline phosphatase (ALP) activity based on Cu(II)-modulated G-quadruplex-based DNAzymes. It is exploiting the strong affinity of Cu(II) for pyrophosphate (PPi) upon which the cofactor PPi is trapped by Cu(II). Hence, the activity of the DNAzyme is inhibited. ALP catalyzes the...
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Full title
Colorimetric determination of the activity of alkaline phosphatase based on the use of Cu(II)-modulated G-quadruplex-based DNAzymes
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Record Identifier
TN_cdi_proquest_miscellaneous_2019804305
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2019804305
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ISSN
0026-3672
E-ISSN
1436-5073
DOI
10.1007/s00604-017-2628-y
