Targeted depletion of lymphotoxin- alpha -expressing T sub(H)1 and T sub(H)17 cells inhibits autoimm...
Targeted depletion of lymphotoxin- alpha -expressing T sub(H)1 and T sub(H)17 cells inhibits autoimmune disease
About this item
Full title
Author / Creator
Chiang, Eugene Y , Kolumam, Ganesh A , Yu, Xin , Francesco, Michelle , Ivelja, Sinisa , Peng, Ivan , Gribling, Peter , Shu, Jean , Lee, Wyne P , Refino, Canio J , Balazs, Mercedesz , Paler-Martinez, Andres , Nguyen, Allen , Young, Judy , Barck, Kai H , Carano, Richard A D , Ferrando, Ron , Diehl, Lauri , Chatterjea, Devavani and Grogan, Jane L
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
Uncontrolled T helper type 1 (T sub(H)1) and T sub(H)17 cells are associated with autoimmune responses. We identify surface lymphotoxin- alpha (LT- alpha ) as common to T sub(H)0, T sub(H)1 and T sub(H)17 cells and employ a unique strategy to target these subsets using a depleting monoclonal antibody (mAb) directed to surface LT- alpha . Depleting...
Alternative Titles
Full title
Targeted depletion of lymphotoxin- alpha -expressing T sub(H)1 and T sub(H)17 cells inhibits autoimmune disease
Authors, Artists and Contributors
Author / Creator
Kolumam, Ganesh A
Yu, Xin
Francesco, Michelle
Ivelja, Sinisa
Peng, Ivan
Gribling, Peter
Shu, Jean
Lee, Wyne P
Refino, Canio J
Balazs, Mercedesz
Paler-Martinez, Andres
Nguyen, Allen
Young, Judy
Barck, Kai H
Carano, Richard A D
Ferrando, Ron
Diehl, Lauri
Chatterjea, Devavani
Grogan, Jane L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_20199549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20199549
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.1984
