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Nanoscale synthesis and affinity ranking

Nanoscale synthesis and affinity ranking

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2031033750

Nanoscale synthesis and affinity ranking

About this item

Full title

Nanoscale synthesis and affinity ranking

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2018-05, Vol.557 (7704), p.228-232

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Most drugs are developed through iterative rounds of chemical synthesis and biochemical testing to optimize the affinity of a particular compound for a protein target of therapeutic interest. This process is challenging because candidate molecules must be selected from a chemical space of more than 10
60
drug-like possibilities
1
, and...

Alternative Titles

Full title

Nanoscale synthesis and affinity ranking

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2031033750

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2031033750

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0056-8

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