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Biglycan promotes the chemotherapy resistance of colon cancer by activating NF-κB signal transductio...

Biglycan promotes the chemotherapy resistance of colon cancer by activating NF-κB signal transductio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2039294617

Biglycan promotes the chemotherapy resistance of colon cancer by activating NF-κB signal transduction

About this item

Full title

Biglycan promotes the chemotherapy resistance of colon cancer by activating NF-κB signal transduction

Publisher

New York: Springer US

Journal title

Molecular and cellular biochemistry, 2018-12, Vol.449 (1-2), p.285-294

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Biglycan (BGN) is overexpressed in cancer stem cells of colon cancer and induces the activation of NF-κB pathway which contributes to the chemotherapy resistance of diverse cancer types. Therefore, we hypothesized that the overexpression of BGN also promoted the development of multiple drug resistance (MDR) in colon cancer via NF-κB pathway. The ex...

Alternative Titles

Full title

Biglycan promotes the chemotherapy resistance of colon cancer by activating NF-κB signal transduction

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2039294617

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2039294617

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-018-3365-1

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