The functions and regulation of the PTEN tumour suppressor: new modes and prospects
The functions and regulation of the PTEN tumour suppressor: new modes and prospects
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
PTEN is a potent tumour suppressor, and its loss of function is frequently observed in both heritable and sporadic cancers. PTEN has phosphatase-dependent and phosphatase-independent (scaffold) activities in the cell and governs a variety of biological processes, including maintenance of genomic stability, cell survival, migration, proliferation an...
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Full title
The functions and regulation of the PTEN tumour suppressor: new modes and prospects
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TN_cdi_proquest_miscellaneous_2049561918
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2049561918
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ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/s41580-018-0015-0
